Endocrine Abstracts

Background: Subacute thyroiditis (SAT) is typically a self-limiting condition, with patients usually returning to normal thyroid function after healing. However, very rarely, Graves’ disease (GD) may develop following SAT. Case presentation: A 50-year-old female patient presented to an outside internal medicine outpatient clinic with anterior neck pain, fatigue, and subclinical fever symptoms. Her medical history included a diagnosis of psoriatic ar...

Background: ChatGPT, an advanced language model, employs sophisticated deep learning techniques to generate human-like responses. It stands as one of the most extensive publicly accessible language models. Despite the longstanding application of Artificial Intelligence (AI) in diverse domains, its application in healthcare raises concerns about the reliability of information. It is equally important to assess whether the provided information is supported by dependable referenc...

Background: Endocrine-related adverse effects of immune check-point inhibitors (ICIs) have been identified in growing number of cancer patients.Case presentation: A 49-year-old male with laryngeal cancer applied to ouroutpatient clinic with weakness, loss of appetite, weight loss, nausea and vomiting for the last three weeks. He was diagnosed with T3N1M0 laryngeal squamous cell cancer seven months before this admission and was given concurrent cisplatin ...

Introduction: Pregnancy occurs relatively rare women with acromegaly. However, in recent years, pregnancy has become more likely to occur in acromegalic women possibly due to improvements in acromegaly treatment, and advanced assisted reproduction techniques.Methods: In this case series, we retrospectively analyzed 11 pregnancies of 8 acromegalic women followed in the university hospital in a time range between 2009–2019. Data were obtained from pa...

Background: The effects of gender-affirming hormonal therapy (GAHT) on body composition in transgender people assigned female at birth (AFAB) have been an area of interest. However, the impact of GAHT on muscle strength remains inadequately studied. We aimed to evaluate early alterations in muscle strength following GAHT in transgender people AFAB by isokinetic dynamometry, the gold standard for assessment of strength.Subjects and Methods: A total of 20 ...

Background: Adult beta-thalassemia patients experience various endocrine complications associated with iron deposition. However, data regarding adrenal insufficiency (AI) are limited.Subjects and Methods: A total of 104 beta-thalassemia patients examined between 2015 and 2024 in our outpatient clinic had at least one measurement of morning serum ACTH and cortisol levels. At the time of presentation, two male patients had already been diagnosed with prima...

Purpose: Acromegalic patients carry a high burden of cardiovascular, metabolic, and neoplastic diseases, but there are limited studies focusing on morphological and functional changes in the kidneys.Methods: The data of acromegalic patients followed over a 43-year period at our center were examined for the development of chronic kidney disease (CKD), renal cysts, and urological cancers.Results: A total of 394 patients (202M/192F, m...